organised crime squad has charged two men over the discovery of a clandestine drug laboratory at a motel in Perth's eastern suburbs.

Police say an investigation into two pharmacy burglaries led investigators to the men who were staying at a motel in Wattle Grove.

In the room, police allegedly found pseudoephedrine-based medications, a large quantity of cold and flu tablets and other drug making materials.

A 31-year-old Gosnells man and a 30-year-old Gosnells man have been charged with two counts of aggravated burglary and attempting to manufacture methylamphetamine.

A 29-year-old Gosnells woman, who was also in the motel room at the time, was charged with breaching her bail.